Visualization of supramolecular structure of Pluronic F127 micellar hydrogels using cryo-TEM

Physicochemical characterization and drug release of thermosensitive hydrogels composed of a hyaluronic acid/pluronic f127 graft.

Pluronic F127 (PF127) is a copolymer which forms thermosensitive hydrogels. Hyaluronic acid (HA) was grafted to PF127 to form a new hydrogel matrix (HP) for delivery of cisplatin and carboplatin. The physicochemical properties and drug delivery of the graft were examined in this study. HP system (20% HP copolymer in water) exhibited a similar sol-gel transition temperature (28.3 degrees C) as P...

Mechanically Tough Pluronic F127/Laponite Nanocomposite Hydrogels from Covalently and Physically Cross-Linked Networks

Cryo-Imaging of Hydrogels Supermolecular Structure

Gelatin, derived from collagen, has both the mechanical properties required for tissue growth, as well the functional domains required for cell binding. In its natural state, gelatin derives its properties from a network of structured, intertwined, triple helical chains, which is stabilized by hydrogen bonds at temperatures below 37 °C. The mechanical properties of such a structure can be furth...

Synthesis and Charaterization of Magensium Oxide Mesoporous Microstructures Using Pluronic F127

Mesoporous  MgO  microstructures  were  synthesized  using magnesium  acetate  tetrahydrate,  ammonium  oxalate  monohydrate and  Pluronic  F127  via  heating  at  40  °C  for  24  h  and  subsequent calcination. The mesoporous structure of magnesium oxide with the specific  surface  area  of  47m2 /g,  pore  volume  0.30  cm3 /g  and  the average pore size 24 nm is produced. According to ...

Structure Change of Polyethersulfone Hollow Fiber Membrane Modified with Pluronic F127, Polyvinylpyrrolidone, and Tetronic 1307

Hydrophilic polyethersulfone (PES) hollow fiber membranes were prepared via non-solvent induced phase separation (NIPS) by addition of polymeric additives as a membrane modifying agent. The effect of the addition of hydrophilic surfactant Pluronic F127, Polyivinylpyrrolidone (PVP), and Tetronic 1307 on the performance of the final PES hollow-fiber membrane was investigated. The morphology of fa...